HISTONE DEACETYLASE INHIBITORS IMPROVE THE REPLICATION OF ONCOLYTIC HERPES SIMPLEX VIRUS IN BREAST CANCER CELLS.

Histone deacetylase inhibitors improve the replication of oncolytic herpes simplex virus in breast cancer cells.

New therapies are needed for metastatic breast cancer patients.Oncolytic herpes simplex virus (oHSV) is an exciting therapy being developed for use against aggressive tumors and established metastases.Although oHSV have been demonstrated safe in clinical trials, a lack of sufficient potency has slowed the clinical application Bathroom Hooks of this

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Influence of thunderstorm cloud on the performance of satellite-to-ground quantum link and parameters simulation

In order to investigate the effect of thunderstorm cloud on the performance of satellite-to-ground quantum link,according to the extinction cross section and the number concentration distribution function of the charged particle in the thunderstorm cloud,the relationships among the particle concentration,charge density and link attenuation of charg

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Analysis of Causative Factors in Oral Cancer

Objective: To analyse different causative factors leading to oral cancer.Study Design: Descriptive type of study.Setting: This study was conducted at the department of E.N.T, DUHS, Karachi.Study Period: From A/C Adaptor Jan 2008, to October 2008.Subjects & Methods: Fifty histopathologically proven patients of oral cancer were selected andanalyzed r

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Reduced Numerical Approximation of Reduced Fluid-Structure Interaction Problems With Applications in Hemodynamics

This paper deals with fast simulations of the hemodynamics in large arteries by considering a reduced model of the associated fluid-structure interaction problem, which in turn allows an additional reduction in terms of the numerical discretisation.The resulting method is both accurate and computationally cheap.This goal Washing Machine Parts is ac

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Value of optical coherence tomography in the detection of macular pathology before the removal of silicone oil

Mohammad Ahmad Rashad, Ahmed Abdel Aliem Mohamed, Asmaa Ismail Ahmed Department Felling Axe of Ophthalmology, Faculty of Medicine, Ain Shams University, Cairo, Egypt Purpose: To assess the pathological macular changes with optical coherence tomography (OCT) before the removal of silicone oil (SiO) in eyes that had undergone pars plana vitrectomy fo

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